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  Biosynthesis of cannabinoids and structural differences between Δ⁹-THC and CBD. Conversion of olivetolic acid to cannabigerolic acid (CBGA) occurs through the use of aromatic prenyltransferase. CBGA acts as the point of differentiation from which cannabinoid-specific FAD-oxidases (THCA synthase & CBDA synthase) convert CBGA to precursor cannabinoid acids. Subsequent decarboxylation of cannabinoid acids results in active cannabinoids. Δ⁹-THC forms a cyclic ring whereas CBD has a hydroxy group resulting three-dimensional structural differences.1       Biosynthesis pathways of cannabinoid, terpenoids, sterols, and flavonoids2,3,4.   Why Should You Pay Attention to Olivetolic Acid? Olivetolic Acid (OA) is more than a benzoic acid derivative—it...

Olivetol (CAS No. 500-66-3) – Product Introduction Hello and welcome to our latest product highlight! Today we’re excited to show Olivetol (CAS 500-66-3) —a high‑quality fine‑chemical intermediate that we supply to global customers, especially in pharmaceutical, research and specialty chemical sectors.   What is Olivetol? Olivetol, with CAS No. 500-66-3, is also known as 5‑pentylresorcinol or 5‑pentyl‑1,3‑benzenediol. Its molecular formula is C₁₁H₁₆O₂ and molar mass ~180.24 g/mol. It is used in chemical synthesis, research applications and as a building block for more complex molecules.   Why Choose Our Olivetol? 1. High Purity – We supply Olivetol with guaranteed assay (e.g., ≥ 99 %) and full documentation (COA, HPLC/NMR) available.2. Reliable Supply &...

Introduction Cannabis sativa L. or marijuana, is a flowering plant that has been used for millennia for food, drugs (both legal and illegal), textile (hemp), and religious purposes. Selective breeding has resulted in numerous C. sativa strains (cultivars) with different properties. For example, hemp strains are fibrous and low in cannabinoids, while medicinal strains are highly flowering and contain both phytonutrients and phytochemicals. Bioactive compounds can be extracted from oils or as aqueous phases from seeds, flowers, leaves, and stems using traditional techniques such as cold-pressing and solvent extraction or by contemporary procedures like ultrasound. Supercritical fluid extraction with carbon dioxide (SFE-CO2) is another technology used in industry to extract p...

Move over, CBD and THC. Discover CBC (Cannabichromene), a non-psychoactive cannabinoid gaining traction for its unique potential and role in the coveted "entourage effect." Learn about the science behind CAS 20675-51-8. Figure 1: The molecular structure of Cannabichromene (CBC). ​ Unveiling CBC: A Minor Cannabinoid with Major Potential​ In the vast and complex world of cannabis phytochemistry, most of the spotlight shines on two players: THC, known for its psychoactive properties, and CBD, celebrated for its wellness applications. However, the cannabis plant produces over a hundred other cannabinoids, each with unique characteristics. Today, we focus on one of the most promising among them: ​Cannabichromene (CBC)​.   CBC, with its ​CAS registry number 20675-51-8, is a non-psychoa...

CBG vs. CBD: Key Differences in Medical Applications​​ Based on the search results, here’s a structured comparison of their medical applications, mechanisms, and unique benefits:​​ Primary Medical Uses ​​CBG​​ CBD​​ Neuroprotection​​: Protects nerve cells in Huntington’s, Parkinson’s, and Alzheimer’s diseases  Anxiety & Stress​​: Reduces generalized anxiety and social anxiety Antimicrobial​​: Combats antibiotic-resistant bacteria (e.g., MRSA)  Pain & Inflammation​​: Alleviates chronic pain (arthritis, fibromyalgia) Digestive Health​​: Reduces inflammation in IBD and stimulates appetite in chemotherapy patients Sleep Support​​: Improves sleep quality via GABA modulation  ​​Glaucoma​​: Lowers intraocular pressure  ​​Epilepsy​​...

​​Cannabichromene (CBC) Anti-Cancer Research: Key Findings and Mechanisms​​ Cannabichromene (CBC), a non-psychoactive phytocannabinoid derived from Cannabis sativa, has emerged as a promising candidate for cancer therapy. Below is a synthesis of its anti-cancer properties and mechanisms based on recent studies:   Anticancer Mechanisms ​​Induction of Cell Death Pathways​​: ​​Apoptosis​​: CBC activates caspase-3/8/9, triggering programmed cell death in pancreatic, breast, and bladder cancer cells  ​​Ferroptosis​​: Upregulates ferroptosis-related genes (e.g., HMOX1) and depletes glutathione, leading to lipid peroxidation in pancreatic cancer models  ​​Autophagy​​: Modulates LC3-II and Beclin-1 expression, promoting cancer cell self-destruction  ​​Receptor Modulation...

Yes. Olivetol treatment demonstrated ​​dose-dependent reductions in triglycerides, cholesterol biosynthesis (via HMG-CoA reductase suppression), and hepatic lipid accumulation​​, effectively ameliorating obesity-induced steatohepatitis. This was corroborated by normalized liver enzyme levels (ALT/AST), indicating significant hepatoprotective effects. These findings establish Olivetol's multi-target therapeutic potential against metabolic dysregulation in obesity, though further research is required to delineate its primary mechanistic actions – including possible synergistic effects with endogenous regulatory pathways – prior to clinical translation.   Figure 1. Olivetol Olivetol exhibits a ​​divergent dose-response​​: low doses reduce hepatic enzymes (hepatoprotecti...