Cannabinol (CAS 521-35-7) is a mildly psychoactive cannabinoid formed primarily through the oxidative degradation of tetrahydrocannabinol (THC), often accumulating in aged cannabis material. It exhibits a unique pharmacological profile characterized by a higher affinity for CB2 receptors than CB1, contributing to its potential therapeutic applications in sleep regulation, pain relief, and as an anti-inflammatory agent. While its psychoactive effects are significantly weaker than THC, its role as a marker for cannabis aging and its emerging bioactivity make it a compound of growing interest in medicinal and analytical research.
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